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SEVPARI-400

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SEVPARI-400

In the management of Hyperphosphatemia in CKD .

SEVPARI 400 is a phosphate binder used to lower high blood phosphorus (phosphate) levels in patients who are on dialysis due to severe kidney disease. Sevelamer works by holding onto phosphate from the diet so that it can pass out of the body. Decreasing blood phosphate levels can help to keep your bones strong, prevent unsafe buildup of minerals in your body, and possibly decrease the risk of heart disease and strokes that can result from high phosphate levels. .

Compositions

  • Sevelamer Carbonate 400mg
  • Packaging: 1X10 , Form: Tablets

Indications

  • SEVPARI 400 is indicated to control serum phosphorus in patients with Chronic Kidney Disease (CKD) on hemodialysis.

Dosages

Based on serum phosphorus level:

  • Phosphorus greater than 5.5 to less than 7.5 mg/dL: 800 mg 3 times a day with meals
  • Phosphorus greater than or equal to 7.5 mg/dL: 1600 mg 3 times a day with meals

Common Side Effects

  • Vomiting
  • Nausea
  • Diarrhea
  • Indigestion
  • Stomach pain
  • Feeling gassy
  • Constipation

Contraindications

SEVPARI 400 is contraindicated in patients with bowel obstruction & patients with known hypersensitivity to sevelamer carbonate or to any of the excipients.

Drug interactions

SEVPARI 400 may interfere with the effectiveness of some drugs (including ciprofloxacin, mycophenolate, thyroid medications such as levothyroxine, among others) by making it more difficult for them to be absorbed by the stomach. 

Disclaimer

This information is for the medical professionals & registered medical practitioners only and must be consumed with the valid prescriptions.